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目的探讨安列克应用在高危剖宫产孕妇中预防产后出血的临床疗效及应用价值。方法选择河北省成安县人民医院妇产科分娩的148例高危剖宫产孕妇,采用随机数字表法分为观察组和对照组,每组74例。对照组给予缩宫素预防产后出血,观察组给予安列克预防产后出血,记录两组临床疗效。结果观察组术中出血(154.28±32.82)ml,术后2h出血(221.38±30.28)ml,术后24h出血(289.37±43.28)ml;对照组术中出血(213.85±46.88)ml,术后2h出血(315.83±45.82)ml,术后24h出血(436.82±64.81)ml,两组差异有统计学意义(P<0.05)。观察组发生颜面潮红2例,恶心呕吐1例,腹泻1例,血压升高2例;对照组发生颜面潮红1例,恶心呕吐2例,腹泻1例,血压升高3例,差异无统计学意义(P>0.05)。结论安列克应用在高危剖宫产孕妇中可以减少产后出血发生,无不良反应,应用安全,值得在临床推广使用。
Objective To investigate the clinical effect and application value of Aileike in preventing postpartum hemorrhage in high risk cesarean section pregnant women. Methods 148 pregnant women with high-risk cesarean section delivered by Department of Obstetrics and Gynecology, People’s Hospital of Cheng’an County, Hebei Province were randomly divided into observation group and control group with 74 cases in each group. The control group was given oxytocin to prevent postpartum hemorrhage. The observation group was given Anilek to prevent postpartum hemorrhage. The clinical efficacy was recorded. Results The intraoperative hemorrhage (154.28 ± 32.82) ml in the observation group was (221.38 ± 30.28) ml at 2 hours after operation, and the bleeding was (289.37 ± 43.28) ml at 24 hours after operation. In the control group, hemorrhage was 213.85 ± 46.88 ml, Hemorrhage (315.83 ± 45.82) ml and postoperative 24h bleeding (436.82 ± 64.81) ml, the difference between the two groups was statistically significant (P <0.05). In the observation group, there were 2 cases of facial flushing, 1 case of nausea and vomiting, 1 case of diarrhea and 2 cases of hypertension. In the control group, there were 1 case of facial flushing, 2 cases of nausea and vomiting, 1 case of diarrhea and 3 cases of hypertension. There was no statistical difference Significance (P> 0.05). Conclusion The application of Anilek in pregnant women with high-risk cesarean section can reduce the incidence of postpartum hemorrhage, no adverse reactions, and is safe to use. It is worth to be popularized in clinic.