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目的分析莫沙必利和埃索美拉唑联合治疗胃食管反流病的临床疗效。方法 76例胃食管反流病患者,按照随机数表法将患者分为:接受埃索美拉唑治疗的对照组、接受莫沙必利和埃索美拉唑联合治疗的观察组,每组38例。比较两组患者的临床症状严重程度、治疗效果差异。结果观察组接受联合治疗后的烧心、反酸、胸骨后疼痛等临床症状严重度评分值均明显低于对照组(P<0.05);观察组的治疗总有效率92.11%明显高于对照组84.21%,差异具有统计学意义(P<0.05)。结论莫沙必利和埃索美拉唑联合疗法有助于减轻胃食管反流病患者的临床症状,提高治疗效果。
Objective To analyze the clinical efficacy of mosapride and esomeprazole in the treatment of gastroesophageal reflux disease. Methods A total of 76 patients with gastroesophageal reflux disease were divided into two groups according to the random number table: control group receiving esomeprazole, observation group receiving combination of mosapride and esomeprazole, and each group 38 example. The severity of clinical symptoms and the difference in treatment effect between the two groups were compared. Results The severity scores of clinical symptoms such as heartburn, acid reflux and post-sternum pain in the observation group were significantly lower than those in the control group (P <0.05). The total effective rate in the observation group was 92.11%, significantly higher than that in the control group 84.21 %, The difference was statistically significant (P <0.05). Conclusion Combination of mosapride and esomeprazole can reduce the clinical symptoms and improve the therapeutic effect in patients with gastroesophageal reflux disease.