业已证明,由于氟化物的掺入,牙齿和骨骼的矿物质化学成分已经有了轻微改变,碳酸盐和柠檬酸盐含量略有降低而镁水平增加,钙磷比例基本维持不变。坚硬组织摄取氟化物的程度取决于摄取和吸收的量.暴露时间长短和类型,地区及有关组织的代谢活性。因而,不论在个体之间还是在富含矿物质结构的组织类型之间的 It has been shown that the chemical composition of the minerals in the teeth and bones has been slightly altered due to the incorporation of fluoride, with a slight decrease in carbonate and citrate levels and an increase in magnesium levels, with the proportion of calcium and phosphorus remaining essentially unchanged. The extent to which fluoride is harvested in hard tissues depends on the amount of uptake and absorption, the duration and type of exposure, and the metabolic activity of the area and the tissues involved. Thus, whether between individuals or between types of tissue rich in mineral structures