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目的探讨老年2型糖尿病(T2DM)患者下肢静脉病变的特点及其相关因素。方法133例老年T2DM患者和125例对照组行双下肢血管二维彩色多普勒超声检查,糖尿病组62例行UA1b、HbA_1c、hsC-RP、FIns及2hIns和C-P,并分析上述指标与下肢静脉病变的关系。结果 (1)糖尿病组静脉瓣功能不全检出率高于对照组(P<0.01);(2)糖尿病组静脉血峰值流速较对照组减慢(P<0.05),小腿部淤血程度重于对照组(P<0.01);(3)糖尿病组静脉瓣功能不全与年龄及动脉硬化相关。结论老年T2DM患者多普勒超声检查下肢静脉病变主要表现为下肢静脉瓣膜功能不全、静脉血峰值流速减慢和小腿静脉淤血;下肢深静脉瓣膜功能不全可能参与糖尿病足的发生和发展,应在糖尿病足的防治中加以重视。
Objective To investigate the characteristics of lower extremity venous diseases in elderly patients with type 2 diabetes mellitus (T2DM) and its related factors. Methods Two-dimensional color Doppler ultrasonography was performed in 133 elderly patients with T2DM and 125 controls. UA1b, HbA1c, hsC-RP, FIns, 2hIns and CP were measured in 62 diabetic patients. The above indexes were compared with those of lower extremity veins The relationship between the lesion. Results (1) The detection rate of venous insufficiency in diabetic group was higher than that in control group (P <0.01); (2) The peak flow velocity of venous blood in diabetic group was slower than that of control group (P <0.05) (P <0.01). (3) Dysfunction of venous valve in diabetic group was related to age and arteriosclerosis. Conclusion Doppler ultrasonography in elderly patients with venous lower extremity venous disease mainly manifested as lower extremity venous valve insufficiency, venous blood flow slowed down and venous congestion; lower extremity deep venous valve insufficiency may be involved in the occurrence and development of diabetic foot should be in diabetes Take full precaution in the prevention and treatment.