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结晶胰岛素锌混悬液(Crystalline Insu-lin Zinc Suspension,Cryst.I.Z.S.)是优良的长效胰岛素注射液。长期以来是我国制药工业上的一项空白。它是利用胰岛素与锌形成结晶后,在中性条件下几乎不溶于水设计而成的一种延效剂型。胰岛素为降糖特效药,测定血糖浓度至今仍是研究其药效的主要手段。为验证新药猪Crys I.Z.S.(本品)的延效作用,实验采用禁食家兔皮下注射本品研究它的降血糖效果和延效作用。
Crystalline Insulin Zinc Suspension (Cryst .I.Z.S.) is an excellent long-acting insulin injection. For a long time is a blank on the pharmaceutical industry in our country. It is the use of insulin and zinc to form crystals, almost insoluble in water under the conditions of the design of a delayed-acting formulations. Insulin is a hypoglycemic agents, determination of blood glucose concentration is still the main means of study of its efficacy. To verify the new drug pig Crys I.Z.S. (the goods) of the delayed effect of experimental use of fasting rabbit subcutaneous injection of this product to study its hypoglycemic effect and delay effect.