子宫平滑肌肉瘤具有从高分化到低分化较宽的形态学谱系变化。在谱系的一端是分化好的肿瘤细胞,由梭形细胞组成,平滑肌细胞容易识别,细胞具有非典型性,核分裂象和凋亡增多。在谱系的另一端肿瘤分化差,除上述表现外,还有大量的间变和多核巨细胞。此外,一些平滑肌肿瘤由HMB-45阳性 Uterine leiomyosarcoma has a wide spectrum of morphological changes from well-differentiated to well-differentiated. At the end of the pedigree is well-differentiated tumor cells composed of spindle cells that are easily identified by smooth muscle cells and have atypical cells with increased mitosis and apoptosis. In the other end of the spectrum of tumor differentiation is poor, in addition to the above performance, there are a large number of intermutation and multinucleated giant cells. In addition, some smooth muscle tumors are positive by HMB-45