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用细胞质分裂阻断微核技术(简称CB微核法)研究了癌细胞的放射敏感性,结果表明;CB 微核法可用来预测癌细胞对重离子和γ射线的放射敏感性,具有省时且成功率高的特点。细胞 受重离子作用后,每双核细胞的微核与剂量的效应关系适合方程 Y= c+ kDn或 Y=c+aD+βD2,受γ射线作用后,每双核细胞的微核与剂量的效应关系适合方程 Y=c+ aD。在相同剂量下,重离子效应高于r射线效应。
The cytosolic cleavage-blocking micronucleus technique (CB micronucleus) was used to study the radiosensitivity of cancer cells. The results showed that CB micronucleus could be used to predict the radiosensitivity of cancer cells to heavy ions and γ-rays. And high success rate characteristics. After the cells are exposed to heavy ions, the relationship between micronuclei and dose per binuclear cell is suitable for the equation Y = c + kDn or Y = c + aD + βD2. c + aD. At the same dose, the heavy ion effect is higher than the r-ray effect.