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Barlow综合征指伴有二尖瓣黏液样变性的原发性二尖瓣瓣叶膨隆,合并或不合并瓣叶脱垂,本病主要累及二尖瓣后叶。其他曾用名包括“收缩中期喀喇音-收缩晚期杂音”、“松软二尖瓣综合征”、“黏液样变性二尖瓣脱垂”、“特发性二尖瓣脱垂”“球形二尖瓣后叶综合征”、“二尖瓣叶脱垂性心肌病”及“二尖瓣脱垂综合征”等。由于现代超声心动图的日益发展和普及,越来越多的二尖瓣脱垂病例被检出,致使“Barlow综合征”成为一种既常用又易被滥用或误用的诊断名称。超声心动图对Barlow综合征的诊断和鉴别具有重要的价值,并可为诊断合并症及评估预后提供帮助。
Barlow’s syndrome refers to primary mitral valve leaflet bulging with mitral myxoid degeneration, with or without valve leaflet prolapse, which primarily affects the posterior mitral valve leaflets. Other former names include “systolic midkine - late systolic murmur,” “soft mitral syndrome,” “myxoid degenerative mitral valve prolapse,” and “idiopathic bicuspid Flap prolapse ”“ spherical mitral valve posterior chamber syndrome ”, “ mitral valve prolapse cardiomyopathy ”and “ mitral valve prolapse syndrome ”and so on. Due to the increasing development and popularity of modern echocardiography, more and more cases of mitral valve prolapse are detected, resulting in “Barlow syndrome” as a commonly used and easily misused or misused diagnostic name. Echocardiography is of great value in the diagnosis and differential diagnosis of Barlow’s syndrome and can help to diagnose the complication and evaluate the prognosis.