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双嘧达莫片是抗血小板聚集药、冠状动脉扩张药。中国药典95版采用分光光度法测定其含量,为了更好地控制其质量。故参照美国药典,采用 HPLC法对其含量进行测定,具有灵敏、简便、结果准确等特点。1 仪器、试药美国 PE 高效液相色谱仪,KQ-100超声波清洗器、磷酸二氢钠、磷酸(广东汕头)甲醇(天津四友)、蒸馏水(蒸馏水厂),双嘧达莫对照品(太行制药厂精制原料粉),双嘧达莫片(哈尔滨制药四厂),批
Dipyridamole tablets are anti-platelet aggregation drugs, coronary dilating drugs. Chinese Pharmacopoeia 95 version of the spectrophotometric determination of its content, in order to better control its quality. Therefore, the reference to the United States Pharmacopoeia, using HPLC method for the determination of its content, with sensitive, simple, accurate results. 1 instruments, reagents United States PE high performance liquid chromatography, KQ-100 ultrasonic cleaner, sodium dihydrogen phosphate, phosphoric acid (Guangdong Shantou) methanol (Tianjin Friends of the four), distilled water (distilled water plant), dipyridamole reference substance Taihang Pharmaceutical Factory refined raw powder), dipyridamole tablets (Harbin Pharmaceutical Factory No. 4), approved