神经生长因子(NGF)系一种多肽激素,为交感神经元和感觉神经元发育所必需,NGF 还参与神经损伤后的再生。它对交感神经元分化的影响,主要表现在促进神经纤维的生长、诱导生成几种与神经递质生物合成有关的酶类,在分化时调控特定基因的开放与关闭。基因表达的序性,即神经元表型 Nerve growth factor (NGF) is a polypeptide hormone that is essential for the development of sympathetic and sensory neurons. NGF is also involved in the regeneration after nerve injury. Its effect on sympathetic neuron differentiation mainly manifests in promoting the growth of nerve fibers, inducing several enzymes related to neurotransmitter biosynthesis, regulating the opening and closing of specific genes during differentiation. The sequence of gene expression, ie, neuronal phenotype