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本文将研究肾病综合征(NS)不同阶段的脂蛋白概况。作者将24例肾功能正常,不同病期的NS儿童分成四组进行研究:Ⅰ组(耐激素组)。有持续蛋白尿、肾活检有局灶性肾小球硬化,未采用激素治疗;Ⅱ组(激素易感)。复发期间未用药治疗,肾活检有微小病变(MC),至少停用激素4周;Ⅲ组(激素易感NS的缓解早期)。肾活检有MC,所有患者都接受强的松治疗,其中2例辅以环磷酰胺治疗;Ⅳ组(激素易感NS的长期缓解期间)。肾活检有MC,患者至少停用激素2个月。结果血清白蛋白、总蛋白:对照组平均血清白蛋白值为4.46±0.36mg/dl,显著高于Ⅰ,Ⅱ组(P<
This article will study the different stages of nephrotic syndrome (NS) lipoprotein profile. The authors of 24 cases of normal renal function, NS disease at different stages of the study were divided into four groups: Ⅰ group (hormone-resistant group). Have persistent proteinuria, renal biopsy with focal glomerulosclerosis, did not use hormone therapy; Ⅱ group (hormone susceptibility). No recurrence during treatment, renal biopsy with minimal change (MC), at least stop the hormone for 4 weeks; Ⅲ group (hormone-susceptible NS early remission). Renal biopsy with MC, all patients were treated with prednisone, of which 2 cases were supplemented with cyclophosphamide; Ⅳ group (hormone-susceptible NS long-term remission period). Kidney biopsy with MC, patients with at least hormone withdrawal for 2 months. Results Serum albumin and total protein: The average serum albumin value of the control group was 4.46 ± 0.36 mg / dl, which was significantly higher than that of the group Ⅰ and Ⅱ (P <