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本文选择鼠抗人肝癌单克隆抗体Hab18与抗癌药物氨甲喋呤(MTX)交联制备Hab-18-MTX结合物,检测该结合物的抗体活性,体外对肿瘤靶细胞的特异性杀伤作用,
In this study, the anti-human hepatoma monoclonal antibody Hab18 was cross-linked with the anticancer drug methotrexate (MTX) to prepare the Hab-18-MTX conjugate, and the antibody activity of the conjugate was measured, and the specific killing effect on tumor target cells in vitro was examined.