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目的探讨血小板计数动态变化在新生儿败血症诊治过程中的临床意义。方法对皖北煤电集团总医院新生儿病房收治的39例新生儿败血症患儿的血小板计数进行动态监测,将血小板计数在感染治疗前、感染时和感染控制后进行比较。结果新生儿败血症感染时与感染治疗前和感染控制后血小板计数比较差异有统计学意义(P<0.01),感染控制后与感染治疗前血小板计数比较差异有统计学意义(P<0.05)。结论血小板减少对新生儿败血症的早期诊断和病情预后判断有重要临床价值。
Objective To investigate the clinical significance of dynamic changes of platelet count in the diagnosis and treatment of neonatal sepsis. Methods Thirty-nine neonates with sepsis were enrolled in the neonatal ward of Wanbei Coal and Methanol Group General Hospital. The platelet count was dynamically monitored before, during, and after infection control. Results There was significant difference in platelet counts between neonates with sepsis infection and before and after infection control (P <0.01). There was significant difference in platelet count between infection control and infection before treatment (P <0.05). Conclusion Thrombocytopenia has important clinical value in the early diagnosis of neonatal sepsis and prognosis of the disease.