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目的:探讨超声结合血清CA125检查在鉴别诊断绝经后卵巢良恶性肿瘤中的价值。方法:2008年8月1日～2010年7月31日,杭州市第一人民医院妇科共收治绝经后卵巢肿物患者122例。术前行超声检查和血清CA125检测,根据超声形态学将卵巢肿物分为囊性、囊实性和实性3类,以CA125值>35 U/ml为阳性。术中发现恶性肿瘤立即根据FIGO分期标准进行手术病理分期。对比术前辅助检查结果与术后病理结果。结果:良性或交界性肿瘤106例,恶性肿瘤16例。单房囊性卵巢肿物为恶性的阴性预测值为100%,囊实性或实性卵巢肿物合并腹水为恶性的阳性预测值为83%。血清CA125值>35 U/ml与CA125值正常者相比,恶性肿瘤可能性增加,差异有统计学意义(P<0.001)。CA125值越高,肿瘤分期也越高。结论:绝经后妇女卵巢肿物为囊实性或实性,且血清CA125值>35 U/ml,卵巢恶性肿瘤风险增高。超声结合CA125检查有助于术前鉴别诊断绝经后卵巢良恶性肿瘤。
Objective: To investigate the value of ultrasound combined with serum CA125 in the differential diagnosis of benign and malignant ovarian tumors. Methods: From August 1, 2008 to July 31, 2010, 122 patients with postmenopausal ovarian masses underwent gynecology in First People’s Hospital of Hangzhou. Preoperative ultrasonic examination and serum CA125 detection, ovarian tumor according to the morphology of ovarian cystic, cystic solid and solid 3 categories, with CA125 value> 35 U / ml was positive. Malignant tumors were found immediately under the operation of FIGO staging staging. Preoperative auxiliary examination results and postoperative pathological results. Results: 106 cases of benign or borderline tumors and 16 cases of malignant tumors. Single-chamber cystic ovarian masses were negative for the malignant predictive value of 100%, cystic solid or solid ovarian masses with ascites malignant positive predictive value of 83%. Serum CA125 values> 35 U / ml and CA125 values were normal, the possibility of malignant tumors increased, the difference was statistically significant (P <0.001). The higher the CA125 value, the higher the tumor stage. Conclusion: The ovarian masses in postmenopausal women are cystic or solid with serum CA125> 35 U / ml and the risk of ovarian cancer is high. Ultrasound combined with CA125 examination helps to differentiate preoperative benign and malignant ovarian tumors.