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目的 评估球结膜下缝合小鼠尾韧带(RTL)对单纯病疹角膜炎(HSK)的预防和治疗效果。方法 从杀死的小鼠身上取下尾部韧带,浸泡于75％酒精液中。然后,缝入球结膜下,距角巩膜缘2mm,沿角巩膜缘绕缝1周。术后观察13月至12年。结果 所有病人都有刺激症状,特别是在活动期。刺激症状多在半月内逐渐减弱或消失最长延续26天。4到14月后RTL被局部组织吸收。116位病人中98位术后观察3年,总有效率为84％。在2年内无复发。结论RTL缝合治疗HSK,操作安全,效果显著,值得推广。
Objective To evaluate the preventive and therapeutic effects of subconjunctival suture mouse tail ligament (RTL) on herpes simplex rash keratitis (HSK). Methods Tail ligaments were removed from the killed mice and soaked in 75% alcohol solution. Then, sewn into the subconjunctival bulb, 2mm from the scleral limbus, and around the limbus along the sclera for 1 week. Postoperative observation of 13 months to 12 years. Results All patients had irritation, especially during the activity phase. Stimulation symptoms more than half a month gradually weakened or disappeared for up to 26 days. After 4 to 14 RTL absorbed by local organizations. Of the 116 patients, 98 were observed for 3 years and the total effective rate was 84%. No recurrence within 2 years. Conclusion RTL suture treatment of HSK, safe operation, the effect is significant, it is worth promoting.