某些病理条件下，白细胞可以大量聚集产生和释放蛋白水解酶、细 胞因子、氧自由基从而加重组织的损伤，并发生与内皮细胞粘附。三大类细胞粘附 分子参与白细胞与内皮细胞的粘附。肿瘤坏死因子－α、白细胞介素－１等细胞因 子调节着白细胞与内皮细胞的粘附。 Under certain pathological conditions, leukocytes can accumulate in large quantities to produce and release proteolytic enzymes, cytokines, and oxygen free radicals, thereby aggravating tissue damage and endothelial cell adhesion. Three types of cell adhesion molecules involved in the adhesion of leukocytes and endothelial cells. Tumor necrosis factor-alpha, interleukin-1 and other cytokines regulate the adhesion of leukocytes to endothelial cells.