论文部分内容阅读
目的:进行补阳还五汤配方简化研究,并比较原方与新方对小鼠肠壁微动脉循环作用差别。方法:以黄芪甲苷含量和出膏率为指标,采用均匀设计法进行补阳还五汤组成简化,再检测两种复方对滴加去甲肾上腺素后小鼠肠壁微动脉循环的影响。结果:新方最佳剂量配伍比例为:当归11 g,川芎11 g,赤芍8.8 g,红花11 g;原方和新方药物能不同程度扩张滴加去甲肾上腺素后小鼠肠壁微动脉。结论:补阳还五汤新方及原方对滴加去甲肾上腺素小鼠肠壁微动脉毛细血管的扩张作用程度基本一致。
OBJECTIVE: To simplify the formula of Buyang Huanwu Decoction and to compare the effects of Huanfang and Xinfang on the micro-arterial circulation in mouse intestinal wall. Methods: Astragaloside content and the rate of ointment as an indicator, using uniform design method for the composition of BYHWD simplified, and then test the two compounds on norepinephrine in mice after the reduction of intestinal micro-arterial circulation. Results: The optimum proportion of the proportion of the new side: Angelica 11 g, Chuanxiong 11 g, red peony 8.8 g, saffron 11 g; the original and the new prescription drugs to varying degrees of expansion of norepinephrine dropped after the intestinal wall Arterioles. Conclusion: The new prescription of Fuyang Huanwu Decoction and the original prescription have the same effect on the dilatation of the capillaries of the intestinal wall microvessels in norepinephrine-treated mice.