本文观察54例正常人和105例消化系统恶性肿瘤及良性疾病病人血清 CA-50的含量。结果表明,癌症病人血清值明显高于正常组和良性疾病组;癌症病人术后血清含量明显降低。CA-50对于胰腺癌、肝癌、结直肠癌、胃癌、胆囊癌均有较高的阳性检出率,且假阳性率很低。提示血清 CA-50检测对肿瘤的诊断、鉴别诊断及估计预后有一定价值。 This article observed the serum CA-50 levels in 54 normal subjects and 105 patients with digestive system malignancy and benign diseases. The results showed that the serum levels of cancer patients were significantly higher than those of normal and benign disease groups; the serum levels of cancer patients were significantly reduced after surgery. CA-50 has a high positive detection rate for pancreatic cancer, liver cancer, colorectal cancer, gastric cancer, and gallbladder cancer, and the false positive rate is very low. It is suggested that the serum CA-50 test has certain value in the diagnosis, differential diagnosis and prognosis of the tumor.