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目的:观察组小剂量奥美拉唑联合帕罗西汀治疗功能性消化不良的疗效方法:选取我院2014年2月—2014年8月收治的功能性消化不良患者120例,随机分为观察组和对照组各60例。两组患者均给予小剂量奥美拉唑治疗。观察组在小剂量奥美拉唑治疗的基础上给予帕罗西汀治疗结果:两组患者治疗后饱胀、反酸、腹痛/腹部不适的症状评分均较治疗前有显著下降,P<0.05;治疗后观察组患者胀、反酸、腹痛/腹部不适的症状评分显著低于对照组,P<0.05。观察组总有效率(93.33%)显著高于对照组(80.00%),P<0.05。结论小剂量的奥美拉唑联合帕罗西汀治疗功能性消化不良较单独使用奥美拉唑治疗,对患者的临床症状改善更为明显,治疗的有效率显著升高,值得临床推广。
OBJECTIVE: To observe the curative effect of low-dose omeprazole combined with paroxetine on functional dyspepsia.Methods: 120 patients with functional dyspepsia admitted in our hospital from February 2014 to August 2014 were randomly divided into observation group and control group The control group of 60 cases. Both groups were given low-dose omeprazole. The observation group received paroxetine treatment on the basis of low-dose omeprazole treatment. The scores of symptoms of full-scale, acid reflux, abdominal pain and abdominal discomfort after treatment in both groups were significantly lower than those before treatment, P <0.05; treatment After the observation group patients with swelling, acid reflux, abdominal pain / abdominal discomfort score was significantly lower than the control group, P <0.05. The total effective rate in the observation group (93.33%) was significantly higher than that in the control group (80.00%), P <0.05. Conclusion Low-dose omeprazole combined with paroxetine treatment of functional dyspepsia alone compared with omeprazole treatment, the clinical symptoms of patients to improve more significantly, the treatment efficiency was significantly increased, worthy of clinical promotion.