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本文用ELISA法检测肺结核、肺外结核、非结核肺部疾病和正常对照共496例血清抗PPD抗体。结果表明结核组的血清抗体水平和阳性率均非常显著高于对照组(P<0.001)。如以P/N(待测标本OD值/阴性血清OD值)>2.1为阳性标准,则本法检测血清抗体对诊断活动性肺结核和肺外结核的敏感性分别为75.4％和67.4％。特异性为94.8％。
In this paper, 496 serum anti-PPD antibodies against tuberculosis, extra-pulmonary tuberculosis, non-tuberculosis lung disease and normal controls were detected by ELISA. The results showed that tuberculosis group serum antibody levels and positive rates were significantly higher than the control group (P <0.001). If the P / N (OD value of the specimen to be tested / OD value of negative serum)> 2.1 as the positive standard, the sensitivity of the method for detecting serum antibodies to diagnosis of active tuberculosis and extrapulmonary tuberculosis were 75.4% and 67.4% respectively. The specificity was 94.8%.