论文部分内容阅读
本文应用二项分布理论分析了京郊某农村82个家庭332人当中HBsAg、抗-HBs、抗-HBc、HBeAg、抗-HBe和抗-HBc IgM阳性者的家庭分布规律。结果显示,HBsAg、HBeAg和抗-HBc IgM阳性者的家庭分布不符合二项分布,有家庭聚集性,抗-HBs,抗-HBc和抗-HBe阳性者的家庭分布符合二项分布,没有家庭聚集性。推测有家庭聚集性的标记和没有家庭聚集性的标记产生的机理不同,流行病学意义亦不相同。遗传-免疫缺陷可能是导致HBsAg、HBeAg和抗-HBc IgM呈家庭聚集性的主要原因。
In this paper, the distribution of family distributions of HBsAg, anti-HBs, anti-HBc, HBeAg, anti-HBe and anti-HBc IgM among 332 families in a rural area of Beijing suburbs was analyzed using binomial distribution theory. The results showed that the distribution of HBsAg, HBeAg and anti-HBc IgM positive families did not meet the binomial distribution, with family aggregation, anti-HBs, anti-HBc and anti-HBe positive family distribution consistent with binomial distribution, no family Aggregation. There is a difference in epidemiological significance between the mechanisms by which the markers of familial aggregation and those without clustering are speculated. Genetic-immunodeficiency may be the leading cause of familial aggregation of HBsAg, HBeAg and anti-HBc IgM.