基层地区新生儿医院内两步听力筛查模式探讨

来源 :中国新生儿科杂志 | 被引量 : 0次 | 上传用户:cuibo1000
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的探讨基层地区医院内两步听力筛查模式的有效性。方法选择2008年11月至2010年4月出生于安阳市妇幼保健院、并接受瞬态诱发性耳声发射筛查的新生儿,医院内第一次初筛单耳或双耳未通过的新生儿于出院前进行第二次初筛或生后42天进行复筛。记录听力筛查时间及双耳筛查结果,按完成听力筛查的时间将新生儿分组,分析通过率与筛查时间的关系、医院内一次初筛和两次初筛后总的通过率,以及医院内第二次初筛与42天复筛两组人群的通过率。结果 (1)完成听力第一次初筛的新生儿共10060例,总体通过率49.1%(4944/10060),通过率随出生后筛查时间的延迟而提高。(2)未通过第一次初筛的新生儿中30.0%(1535/5116)出院前接受第二次初筛,通过率78.4%(1204/1535),两次初筛后总体通过率61.1%(6148/10060),与一次初筛通过率(49.1%)差异有统计学意义(χ2=291.3,P<0.001)。(3)未通过医院内听力初筛的婴儿中39.1%(1531/3912)于42天接受复筛,通过率92.7%(1420/1531),与医院内第二次初筛通过率(78.4%)差异有统计学意义(χ2=127.3,P<0.001)。结论新生儿听力筛查时间是影响通过率的关键因素,随着出生后筛查时间的延迟,初筛通过率逐步提高;医院内两步筛查可提高初筛通过率,但医院内第二次初筛通过率低于42天复筛通过率。 Objective To investigate the effectiveness of two-step audiometric screening in hospitals in primary areas. Methods Neonates born in Anyang MCH Hospital from November 2008 to April 2010 were enrolled in this study. The neonates who had undergone transient screening for otoacoustic emissions were enrolled in the hospital for the first time. Children in the second pre-discharge screening or 42 days after birth for re-screening. Record hearing screening time and binaural screening results, according to the time to complete hearing screening of newborns, the analysis of the relationship between the pass rate and screening time, the hospital once the initial screening and the total pass rate after two primary screening, As well as the second screening of the hospital and 42 days of re-screening two groups of people through rate. Results (1) The total number of newborns who completed the first screening of hearing was 10060. The overall passing rate was 49.1% (4944/10060). The passing rate increased with the delay of screening after birth. (2) 30.0% (1535/5116) of the newborns who did not pass the first primary screening received the second pre-discharge screening rate of 78.4% (1204/1535), the overall pass rate after two primary screening was 61.1% (6148/10060), which was significantly different from the primary screening rate (49.1%) (χ2 = 291.3, P <0.001). (3) 39.1% (1531/3912) of the infants who did not pass the first screening in the hospital received re-screening on the 42nd day, the pass rate was 92.7% (1420/1531), the second pass screening rate in the hospital (78.4% ) Difference was statistically significant (χ2 = 127.3, P <0.001). Conclusion The neonatal hearing screening time is the key factor affecting the passing rate. With the delay of screening time after birth, the screening rate gradually increased; two-step screening in hospital can improve the screening rate, but the hospital second Secondary screening rate of less than 42 days through the screening rate.
其他文献
目的:提供ΦC31整合酶研究所需的大量纯化蛋白质及特异性抗体.方法:将编码ΦC31整合酶的ORF插入到pET22b+载体构建表达质粒并转化E.coli B121(DE3),用IPTG诱导表达His-C31整
目的 探讨儿童急性淋巴细胞白血病(ALL)中A激酶锚定蛋白12(AKAP12)基因启动子区域CpG岛异常甲基化情况及其与临床病理参数之间的关系.方法 用甲基化特异性聚合酶链反应(MSP)
目的 研究壳寡糖减弱乙醇时人胚胎肝细胞(L02细胞)损伤的原因. 方法 采用MTT法检测壳寡糖减弱乙醇对L02细胞的损伤;结合RT-PCR和Western blot方法分析壳寡糖的保护作用. 结果
文章研究了多元混合物料在不同混合比例条件下厌氧消化性能.以餐厨与鸡粪混合、果蔬与鸡粪混合、餐厨果蔬(TS计,8∶5)与鸡粪混合为原料,三种混合处理的混合比例均分别为4∶1,
传统的污水处理工艺对内分泌干扰物(EDCs)的去除效果不稳定,而且不能彻底去除水中EDCs,使之达到产生危害的阈值浓度以下.大部分EDCs是分子量在200~500 Da之间的有机物,这些污
采用16S rDNA-RFLP及序列分析方法,对分离自黄华属的披针叶黄华、喀什黄华和光叶黄华根瘤菌进行分析研究.结果表明,分离得到的33株根瘤菌在种水平上具有丰富的遗传多样性,它
目的 诱变选育阿维拉霉素高产菌株. 方法 紫外线随机诱变结合阿维拉霉素、2-氧-D-葡萄糖和高浓度CaCl2抗性筛选的推理选育方案. 结果 通过选育获得了抗CaCl2的高产菌株Avl-10
目的 构建人源抗乙型肝炎病毒表面抗原(HBsg)×人源化抗CD3双特异双链抗体(aiabody)与重组复合干扰素(consensus Interferon, cIFN)的融合蛋白(抗HBsAg×抗CD3 diabody-cIFN,
急性肝衰竭和晚期肝病严重危害人类的健康,原位肝移植是目前治疗这类疾病惟一有效的治疗方法,却受到了供肝缺乏的限制.肝细胞移植、生物人工肝以及组织工程肝是潜在的解决办
目的 探索培养传代后鸡胚原始生殖细胞(EPGCs)的多向分化潜能,比较不同诱导程序、不同特异性化学诱导剂及其协同作用.方法 分别获取发育至19期和28期的鸡胚PGCs,体外培养传代