Gold在1950年曾指出奎尼丁与洋地黄兼用是危险的。但是,这两种药物又常常联合应用。自1973年广泛应用洋地黄放射免疫测定以来,作者注意到接受地高辛治疗而病情稳定的病人,再投用奎尼丁时血清地高辛浓度可升高。在并用奎尼丁治疗期间出现的胃肠道反应,可因减少地高辛的剂量而得以绥解。本文采取回顾性研究,试图搞清奎尼丁和地高辛之间的相互影响。 Gold in 1950 pointed out that quinidine and digitalis combination is dangerous. However, these two drugs are often combined. Since the widespread use of digitalis radioimmunoassay in 1973, the authors noted that patients treated with digoxin had stable serum digoxin concentrations after reinstatement of quinidine. Gastrointestinal reactions that occur during concurrent quinidine administration can be resolved by reducing the dose of digoxin. This article takes a retrospective study to try to figure out the interaction between quinidine and digoxin.