类固醇性糖尿病(steroid diabetes)是因肾上腺皮质醣类固醇过多而引起的糖尿状态。醣类固醇与醣代谢紊乱的关系早已肯定:Long与Lukens二氏的实验指出,将切除胰腺的猫的肾上腺切除,可使糖尿病转轻;Cushing氏综合征有49—55%示葡萄糖耐量减低,并有26～35%发生糖尿;长期、大量用皮质素治疗可致糖尿。为说明此类糖尿病的临床特征,特报告3例Prednisolone引起的糖尿患者,供作讨论。 Steroid diabetes is a glucosuria induced by excess cortisol in the adrenal cortex. The relationship between carbohydrate steroids and glucose metabolism has long been affirmed: Long and Lukens two’s experiment shows that resection of the cat’s adrenalectomy can make the diabetes turn light; 49-55% of Cushing’s syndrome showed impaired glucose tolerance and 26 ~ 35% of occurrence of diabetes; long-term, large amounts of cortisol treatment can cause diabetes. To illustrate the clinical features of this type of diabetes, 3 prednisolone-induced diabetic patients are reported for discussion.