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银杏叶提取物近年来被用于治疗脑功能障碍,它所含有的萜类似物白果内酯(BB)是银杏叶的特有成分,为提取物的活性主体之一。研究发现BB对各种药物诱发的小鼠痉挛有抑制作用,并且给予BB可使小鼠海马的GABA浓度升高。因而推测BB的解痉作用与GABA神经系有关。
Ginkgo biloba extract has been used for the treatment of brain dysfunction in recent years. The quinone lactone (BB) contained in it is a unique component of Ginkgo biloba leaf and is one of the main active ingredients of the extract. Studies have found that BB has inhibitory effects on mice induced by various drugs, and that administration of BB can increase the concentration of GABA in the mouse hippocampus. Therefore, it is speculated that the antispasmodic effect of BB is related to the GABA nervous system.