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本文报告以脱水剂为主和以脑血管扩张剂作治疗的急性脑血管病各60例的疗效对比观察.研究采取前瞻性、随机性的方法进行.两组病例在发病,年龄、性别、病种上均相似,但重型病例数脱水剂组明显多于脑血管扩张剂组.脱水剂组用20%甘露醇250ml静滴、6～12小时1次,部分病例与速尿交替使用,少数病例加用地塞米松;脑血管扩张剂用罂粟硷,血管舒缓素,654-2等.治疗结果:①总有效率,轻型和中型的有效率脱水剂组均优于脑血管扩张剂组,但在重型病例组有效率差异显著;②平均住院天数:轻、中、重型病例脱水剂组均短于脑血管扩张剂组;③急性期死亡数也以脱水剂组为低;④并发症数脱水剂组比脑血管扩张剂组少,以并发感染的减少为最明显.故对急性脑血管梗塞,特别是重型病例、应首先考虑使用脱水剂.本文讨讨了脱水剂治疗急性脑梗塞的有关机制问题.
This article reports the comparison of the curative effect between 60 cases of acute cerebrovascular disease which is mainly treated by dehydrating agent and treated by cerebral vasodilator.Studies are prospective and random.The incidence of disease, age, sex, disease However, the number of severe cases was significantly higher than that of cerebral vasodilators in the dehydrating agent group, and the dehydrating agent group was intravenously administered with 250ml of 20% mannitol once for 6 ~ 12 hours. In some cases, furosemide was used interchangeably with a few cases Plus dexamethasone; cerebrovascular vasodilator with papaverine, blood kallikrein, 654-2, etc. Treatment outcome: ① total effective rate, light and medium efficiency dehydration group were better than the group of cerebral vasodilators, but in the The effective rate of the severe cases was significantly different; ②the average hospitalization days: the light, medium and heavy cases of dehydrating agent group were shorter than the cerebral vasodilator group; ③ the number of deaths in the acute phase was also lower in the dehydrating agent group; ④ the number of complications dehydrating agent Group is less than cerebral vasodilator group, the reduction of concurrent infection is the most obvious.Therefore, acute cerebral infarction, especially in severe cases, should first consider the use of dehydrating agent.This paper discussed the mechanism of dehydration agent for the treatment of acute cerebral infarction problem.