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目的:探讨米非司酮治疗胎盘粘连的综合疗效。方法:选取入院治疗的236例胎盘粘连患者为研究对象,分成治疗组和对照组各118例。治疗组患者给予米非司酮25 mg口服,每日2次,连续7天;对照组患者给予催产素10 U肌注,每日2次。结果:两组患者治疗后12和24 h的阴道出血量差异无统计学意义(P>0.05),而72 h的阴道出血量治疗组低于对照组,差异有统计学意义(P<0.05);1周后治疗组阴道停止出血70例,占59.32%,对照组14例,占11.86%,差异有统计学意义(P<0.05)。结论:应用米非司酮治疗胎盘粘连效果较好,属于无创、安全、便捷的治疗方法。
Objective: To investigate the comprehensive efficacy of mifepristone in treating placenta adhesion. Methods: A total of 236 patients with placental adhesion were selected as study subjects and divided into treatment group and control group with 118 cases each. Patients in the treatment group were given mifepristone 25 mg orally twice daily for 7 days. Patients in the control group were given 10 U of oxytocin intramuscular injection twice daily. Results: There was no significant difference in the amount of vaginal bleeding between the two groups at 12 and 24 hours after treatment (P> 0.05), while the amount of vaginal bleeding at 72 hours was lower in the treatment group than in the control group (P <0.05) 70 cases (59.32%) died of vaginal bleeding one week later in treatment group and 14 cases (11.86%) in control group, the difference was statistically significant (P <0.05). Conclusion: The application of mifepristone in the treatment of placenta adhesion is better, which is a non-invasive, safe and convenient treatment.