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哌嗪 (ｐｉｐｅｒａｚｉｎｅ)广泛用于抗肠蠕虫药 ,它在模拟胃液 (ＳＧＪ)条件下可部分转化为Ｎ ,Ｎ 二亚硝基哌嗪 (Ｎ ,Ｎ ｄｉｎｉｔｒｏｓｏｐｉｐｅｒａｚｉｎｅ ,ＤＮＰＺ) ,它具有很强的致癌性。本文介绍简单和专一的反相ＨＰＬＣ法测定模拟胃液中产生的ＤＮＰＺ ,ＵＶ检
Piperazine is widely used as an anti-intestinal worm drug and is partially converted to N, N dinitrosopiperazine (DNPZ) under the conditions of simulated gastric fluid (SGJ). It has strong carcinogenicity Sex. This article describes a simple and specific reverse phase HPLC method for the determination of DNPZ produced in simulated gastric fluid, UV