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目的评价降钙素原(PCT)在诊断感染性腹泻病患儿的临床价值。方法选择河南科技大学三附院东方医院2007年1月～2010年1月住院的感染性腹泻病患儿69例,根据病情分为中毒性细菌性痢疾、普通型细菌性痢疾组及轮状病毒肠炎组。检测PCT及C反应蛋白(CRP)变化,并对资料进行统计分析。结果中毒性细菌性痢疾组PCT阳性率96.0%,CRP阳性率88.0%,普通型细菌性痢疾组PCT阳性率28.0%、CRP阳性率12.0%,轮状病毒肠炎组PCT阳性率5.6%、CRP阳性率0。结论 PCT和CRP在感染性腹泻病的诊治过程中的变化是相似的,但PCT对细菌感染的变化较CRP更敏感,两者不能鉴别肠道病毒与普通型细菌性痢疾。
Objective To evaluate the clinical value of procalcitonin (PCT) in the diagnosis of children with infectious diarrhea. Methods 69 patients with infectious diarrhea admitted to Oriental Hospital of Third Affiliated Hospital of Henan University of Science and Technology from January 2007 to January 2010 were divided into three groups according to the disease, such as toxic bacillary dysentery, common bacillary dysentery and rotavirus Enteritis group. Detection of PCT and C-reactive protein (CRP) changes, and statistical analysis of the data. Results The positive rate of PCT was 96.0% and the positive rate of CRP was 88.0%. The positive rate of PCT was 28.0%, the positive rate of CRP was 12.0%, the positive rate of PCT was 5.6% in rotavirus enteritis group and the positive rate of CRP was Rate 0. Conclusions The changes of PCT and CRP in the diagnosis and treatment of infectious diarrhea are similar, but PCT is more sensitive to bacterial infection than CRP. Both of them can not distinguish enterovirus from common bacillary dysentery.