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淀粉样变性,临床表现形式多样,一般是由于蛋白样物质,细纤维、嗜酸细胞、细胞外透明物质的沉积而引起。确诊靠活检。常在尸检时取组织,作特殊染色经组织学鉴定而确诊。本症以脾破裂的急腹症来急诊。 患者,男性、49岁,因左上腹进行性腹痛数日而入院。一周来无腹部外伤史。体检发现肝脏肿大。腹部有压痛及反跳痛。患者血压80/40毫米汞柱,作剖腹探查证实为脾破裂。切除脾脏时,作肝、脾活检,诊断为原发性淀粉样变性。
Amyloidosis, a variety of clinical manifestations, is generally due to the deposition of protein-like substances, fine fibers, eosinophils, extracellular substances. Confirmed by biopsy. Often taken at necropsy tissue, for special staining confirmed by histological diagnosis. The disease to acute spleen rupture of the emergency. Patient, male, 49 years old, admitted to hospital for a few days for progressive abdominal pain in the left upper quadrant. No history of abdominal trauma in a week. Physical examination found that the liver enlargement. Abdominal tenderness and rebound tenderness. Patients with blood pressure 80/40 mm Hg, laparotomy proved spleen rupture. Excision of the spleen, liver and spleen biopsy, diagnosis of primary amyloidosis.