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自Luttermoser报告甘油能增加口服吐酒石或腹腔注射锑酚对曼氏血吸虫病的疗效后,作者等经动物试验证明甘油亦能增进肌肉或腹腔注射锑酚及吐酒石对小白鼠的日本血吸虫病的疗效。鉴于近年来在血吸虫病的临床治疗中已广泛地推行了短程疗法,进一步研究甘油对锑剂短程疗法的增效作用,将有助于临床应用的参考,乃先后用小白鼠及家兔作了如下实验。
Since Luttermoser reports that glycerol can increase the efficacy of oral tartar or antiinfective ip injection of Schistosoma mansoni, animal experiments have shown that glycerol can also enhance the effects of intramuscular or intraperitoneal injection of anti-phenols and tartarol on Schistosoma japonicum Sickness effect. In view of the fact that short-course therapy has been widely implemented in the clinical treatment of schistosomiasis in recent years, further studies on the synergistic effect of glycerol on the antimony agent short-course therapy will serve as a reference for clinical application and are made using mice and rabbits successively The following experiment.