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目的:分析儿茶酚胺增多症的代谢状况,提高其临床诊治水平和认识。方法:收集分析1998年1月至2008年4月新疆维吾尔自治区人民医院收治的58例儿茶酚胺增多症的临床资料。结果:58例儿茶酚胺增多症患者中肾上腺嗜铬细胞瘤46例(79.3%),肾上腺外嗜铬细胞瘤11例(19.0%),肾上腺增生1例(1.7%);临床有典型“三联征”8例(13.8%),表现为“三联征”症状之一的有48例(82.8%),血压升高的48例(82.8%),伴有糖代谢异常的共19例(32.8%),高脂血症16例(27.6%),低钾血症7例(12.1%);CT检查阳性58例(100%)。结论:儿茶酚胺增多症可表现为血糖、血脂、钾离子代谢紊乱,这对于其诊断具有一定价值。
Objective: To analyze the metabolic status of catecholamine hypersecretion and to improve its clinical diagnosis and treatment. Methods: The clinical data of 58 cases of catecholaminemia admitted to People’s Hospital of Xinjiang Uyghur Autonomous Region from January 1998 to April 2008 were collected and analyzed. Results: Of the 58 patients with catecholaminemia, 46 (79.3%) had adrenal pheochromocytoma, 11 (19.0%) had adrenal pheochromocytoma and 1 (1.7%) had adrenal hyperplasia. Eight patients (13.8%) showed symptoms of “triple symptoms” in 48 cases (82.8%), 48 cases of elevated blood pressure (82.8%), with a total of 19 cases of glucose metabolism abnormalities 32.8%), hyperlipidemia in 16 cases (27.6%) and hypokalemia in 7 cases (12.1%). CT was positive in 58 cases (100%). Conclusion: The increase of catecholamine may be manifested as disorder of blood glucose, blood lipid and potassium ion metabolism, which has some value for its diagnosis.