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目的了解新疆HIV母婴阻断的现况,为做好母婴阻断工作提供科学依据。方法对2011─2012年新疆伊宁市、喀什市、伊宁县妇幼保健院的135例HIV抗体确认阳性的孕产妇及其婴幼儿服药情况及感染率进行调查。结果婴幼儿HIV感染率处于较低水平,阳性孕产妇服用阻断药物及配合人工喂养效果显著,但用药方案及用药时间较混乱;孕产妇用药方案多达14种,停药时间长短不一;新生儿用药方案较一致,但服药时间长可达46天,短可致7天,较为混乱;实验室干血斑检测婴幼儿HIV感染率3.70%。结论新疆HIV母婴阻断的效果明显,需要对负责随访的人员进行相关理论知识的培训,医护人员的知识水平和孕产妇用药的理念有待进一步提高和改变。
Objective To understand the status of HIV maternal and infant blockage in Xinjiang and provide a scientific basis for doing the maternal and child blockade. Methods A total of 135 HIV-positive pregnant women, infants and toddlers in Yining, Kashgar and Yining Maternal and Child Health Care Hospitals in Xinjiang Uygur Autonomous Region from 2011 to 2012 were investigated. Results The prevalence of HIV infection in infants and young children was relatively low. Positive pregnant women taking obstructive drugs and artificial feeding had a significant effect, but the dosage regimen and medication time were chaotic. As many as 14 kinds of medication were used in pregnant women and the duration of withdrawal was different. Neonatal medication program more consistent, but taking a long time up to 46 days, short may cause 7 days, more confusing; laboratory dry blood spot detection of infant HIV infection rate of 3.70%. Conclusion The effect of HIV maternal and infant blockage in Xinjiang is obvious. The relevant theoretical knowledge needs to be trained for the follow-up personnel. The knowledge level of medical staff and the concept of maternal drug need to be further improved and changed.