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目的观察人用Vero细胞狂犬病疫苗的接种反应。方法对810名观察对象采用0、3、7、14、28d共接种5针的程序进行暴露后免疫,观察接种疫苗30min内的即时反应,及24h、72h、15d和3个月内的反应。结果810名观察对象接种人用Vero细胞狂犬病疫苗后,均未发生即时反应,局部及全身一般反应发生率分别为1.85%和1.60%。结论接种人用Vero细胞狂犬病疫苗具有良好的安全性。
Objective To observe the vaccination response of human rabies vaccine using Vero cells. Methods Eighty-one observers were vaccinated with 0, 5, 7, 14, 28d co-inoculation for 5 days. The immediate response within 30 minutes and the responses within 24h, 72h, 15d and 3 months were observed. Results 810 subjects were vaccinated with human Vero cells rabies vaccine, no immediate response, local and systemic general response rates were 1.85% and 1.60%. Conclusion Vaccines against human rabies vaccination with Vero cells have good safety.