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自身免疫性溶血性贫血(AIHA)中属温抗体型者,其红细胞被IgG类自身抗体致敏,并被巨噬细胞过早破坏。作者等曾报道炔羟雄烯异恶唑(Danazol)治疗特发性血小板减少性紫癜有效。本文报道应用该药治疗15例AIHA的结果。7例为特发性AIHA,5例伴有非恶性疾病(系统性红斑狼疮3例,结节病1例,胆汁性肝硬化1例),3例原有肿瘤。
In autoimmune hemolytic anemia (AIHA) is a warm antibody type, the red blood cells were sensitized by IgG autoantibodies, and premature destruction by macrophages. The authors have reported that alkyne androsterone isoxazole (Danazol) treatment of idiopathic thrombocytopenic purpura effective. This article reports the application of the drug treatment of 15 cases of AIHA results. 7 cases were idiopathic AIHA, 5 cases were associated with non-malignant disease (3 cases of systemic lupus erythematosus, 1 case of sarcoidosis, 1 case of biliary cirrhosis) and 3 cases of original tumor.