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目的:观察氟比洛芬酯超前镇痛对口腔颌面手术麻醉效果的影响。方法:将口腔颌面手术80例随机分为观察组和对照组各40例。观察组麻醉诱导前静脉注射氟比洛芬酯2mg/kg,对照组静脉注射等量生理盐水。术中采用静脉复合全麻,比较两组各时间节点平均动脉压、手术时间,麻醉药总用量和术后苏醒期并发症的发生率。结果:观察组气管拔管时平均动脉压显著低于对照组(P<0.05),其余各时间节点两组比较,差异不显著(P>0.05)。观察组术中丙泊酚、瑞芬太尼总用量显著少于对照组(P<0.05),苯磺顺阿曲库铵(顺式阿曲库铵)总用量、拔管时间两组比较,差异不显著(P>0.05)。观察组苏醒期并发症发生率显著低于对照组(P<0.05)。结论:采用氟比洛芬酯超前镇痛,可减少麻醉药总用量,降低全麻气管拔管时平均动脉压。
Objective: To observe the effect of flurbiprofen axetil on analgesia of oral and maxillofacial surgery. Methods: 80 cases of oral and maxillofacial surgery were randomly divided into observation group and control group, 40 cases each. The observation group received intravenous injection of flurbiprofen axetil 2 mg / kg before induction of anesthesia, and the control group received intravenous injection of equal volume of saline. Intraoperative intravenous composite anesthesia, mean arterial pressure, operative time, the total amount of anesthesia and postoperative recovery rate comparisons between two groups were compared. Results: The mean arterial pressure of tracheal extubation in observation group was significantly lower than that in control group (P <0.05). The other two groups showed no significant difference (P> 0.05). The total amount of propofol and remifentanil in the observation group was significantly less than that of the control group (P <0.05), the total amount of cisatracurium (cisatracurium) The difference was not significant (P> 0.05). The incidence of morbidity in the observation group was significantly lower than that in the control group (P <0.05). Conclusion: The use of flurbiprofen axetil prednisolone can reduce the total amount of anesthetics and reduce mean arterial pressure during tracheal extubation.