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目的:探讨CT对胃肠道间质瘤(GIST)的诊断价值。回顾性分析14例经免疫组织化学证实的GIST的CT表现。方法:14例GIST中,良性6例,恶性8例。位于胃8例,小肠4例,结肠1例,肠系膜1例。肿块直径约(11.2±2.6)cm。位于消化道的13例中,腔外生长者9例(69.2%),腔内、外生长者4例(30.8%)。结果:CT检查者中,肿块密度均匀5例,不均匀9例。增强后均匀强化4例,不均匀强化10例。6例影像学随访检出复发4例,其中3例经口服STI-571治疗患者中2例观察到肿瘤缩小和液化,1例肿瘤增大。结论:GIST的CT表现有一定特征性。消化道来源的腔外生长肿块,伴有囊变、坏死或与消化道相通和增强后均匀或不均匀强化,应考虑GIST可能。CT在GIST诊断和随访中起重要作用。
Objective: To investigate the diagnostic value of CT in gastrointestinal stromal tumors (GIST). The CT findings of 14 cases of GIST confirmed by immunohistochemistry were analyzed retrospectively. Methods: Among the 14 cases of GIST, 6 were benign and 8 were malignant. Located in the stomach 8 cases, 4 cases of small intestine, colon 1 case, 1 case of mesentery. Mass diameter of about (11.2 ± 2.6) cm. Among the 13 cases located in the digestive tract, 9 (69.2%) had extracavitary growth and 4 (30.8%) had intracavitary and extrinsic growth. Results: In the CT examination, the mass density was uniform in 5 cases and inhomogeneous in 9 cases. After the enhancement, 4 cases were uniformly strengthened and 10 cases were unevenly strengthened. Of the 6 cases, 4 cases were found with recurrence, of which 3 cases had tumor shrinkage and liquefaction in 2 of the 3 patients treated with oral STI-571, and 1 case of tumor increased. Conclusion: The CT findings of GIST have certain characteristics. Gases derived from extraluminal growth of the digestive tract, with cystic degeneration, necrosis or gastrointestinal interlinked and enhanced after the uniform or uneven enhancement should be considered GIST. CT plays an important role in the diagnosis and follow-up of GIST.