肢端肥大症合并严重糖尿病酮症酸中毒(DKA)临床上不多见。我们收治2例,报告如下: 例1,男性,30岁,因肢端肥大10年,伴多饮、多尿、多食半月,于1991年11月20日入院。患者于1981年末开始手足逐渐增大、宽厚,颜面相貌变得粗陋,皮肤粗厚,疲乏无力,近年来手足仍有增大,伴头痛、视力减退,入院前半月出现口渴、多饮、多尿、多食,空腹血糖29.69mmool/L、尿糖(卌)、尿酮体(卅)。诊断:肢端肥大症合并DKA。体验T36℃、P84次/分、R20次/分,BP17.3/9.3kPa,神清、皮肤弹性差、面貌粗陋、手足粗厚肥大,双眼球水平震颤,甲状腺不大,无血管杂音,心、肺、肝、脾无异常,蝶鞍 Acromegaly with severe diabetic ketoacidosis (DKA) clinically rare. We admitted 2 cases, the report is as follows: Example 1, male, 30 years old, due to acromegaly for 10 years, with more drinks, polyuria, eat more than half a month, was admitted on November 20, 1991. Patients began to increase in their hands and feet in late 1981, generous, face became rough, thick skin, tired and weak, hand, foot and hand have increased in recent years, with headache, vision loss, the first half before admission thirst, drink more Urine, eat more, fasting blood glucose 29.69mmool / L, urine sugar (卌), urinary ketone body (卅). Diagnosis: Acromegaly combined with DKA. Experience T36 ℃, P84 times / min, R20 beats / min, BP17.3 / 9.3kPa, Shen Qing, the skin elasticity is poor, the appearance is primitive, the thick hand-foot hypertrophy, the tremor of both eyes, the thyroid gland is small, No abnormal lung, liver, spleen, sella