噻苯达唑(Thiabendazole)自1961年已作为一种广谱的抗肠虫剂应用,以后曾在试管内及动物中被证明对须癣毛菌有抗真菌作用。对人类癣菌病有人以4％噻苯达唑制剂局部外用,但作用不明显。另外有人用2％噻苯达唑90％二甲基亚砜溶液治疗两例掌黑癣,得到完全治愈,但用作对比的4％油膏则无效。对深都真菌病,有人以口服噻苯达唑治疗着色真菌病,结果有的病人长期服药后损害消失,有的在停药后复发。有1例以噻苯达唑粉剂外用,治疗着色真菌病溃疡,经7个月治愈。 Thiabendazole has been used as a broad-spectrum antihelminthic agent since 1961 and has subsequently been shown to have an antifungal effect against Trichophyton mentagrophytes in vitro and in animals. Some people with dermatophytosis 4% thiabendazole topical preparations, but the effect is not obvious. Others were treated with 2% thiabendazole 90% dimethylsulfoxide solution of two cases of treatment of psoriasis, was completely cured, but as a reference 4% ointment is invalid. For all fungal diseases, someone was treated with oral thiabendazole colored fungal disease, the results of some patients after long-term damage disappeared, and some relapse after withdrawal. 1 case of thiabendazole powder topical treatment of fungal fungal ulcer, after 7 months of cure.