来源于线粒体的肌酸激酶同工酶(CK-mit)的存在,首先在大鼠的心肌及骨骼肌,随后在兔心肌及人尸解材料得到证实。在醋纤薄膜电泳中,CK-mit从CK-MM向阴极移动。据报道指出,当深部组织损伤时,CK-mit被释入血清。 1978年,作者从538例病人采集了1009个血清标本,分别测定了总肌酸激酶(CK)和CK同工酶。作者认为这种同工酶与其他作者报道的CK-mit相同,并对14例病人进一步作了血清乳酸脱氢酶 The presence of mitochondrial creatine kinase isoenzyme (CK-mit) was first confirmed in rat myocardium and skeletal muscle and subsequently in rabbit myocardial and human autopsy material. In cellulose acetate membrane electrophoresis, CK-mit moves from CK-MM to the cathode. It has been reported that CK-mit is released into the serum when deep tissue is damaged. In 1978, the authors collected 1009 serum samples from 538 patients and measured total creatine kinase (CK) and CK isoenzyme, respectively. The authors consider this isoenzyme as CK-mit reported by other authors, and 14 patients were further treated with serum lactate dehydrogenase