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继发肺部感染(简称“肺部感染”)是造成和促进结核病患者死亡的重要因素.耐药结核病患者病程长、肺部病变广泛,是构成呼吸道继发感染的基础;同时患者长期住院、使用广谱抗生素、进行侵袭性操作易发生医院内下呼吸道感染.继发肺部感染将加重耐药肺结核患者肺组织损伤,加重耐药肺结核耐药程度,加重患者营养不良,从而降低患者对治疗的依从性.因此,对耐药肺结核患者要加强预防继发肺部感染的管理.“,”Secondary pulmonary infection is the important factors to cause and promote tuberculosis (TB) patients death.The patients with drug-resistant TB have a long course and a wide range of lung lesions,which is the basis for the formation of secondary infection of respiratory tract.Meanwhile,the patients with long-term hospitalization,the use of broad-spectrum antibiotics,invasive operation prone to nosocomial lower respiratory tract infection.Secondary pulmonary infection can aggravate lung tissue injury of patients with drug-resistant TB;increase the degree of drug-resistant TB and make the patients malnutrition heavier.All of this will reduce the patients compliance.Therefore,secondary pulmonary infection of patients with drug-resistant pulmonary TB should be prevent and manage strengthenly.