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目的观察苯那普利的降压效果及对肝、肾功能的影响。方法４４例高血压患者用药前进行２４ｈ动态血压监测，并检查肝、肾功能及血糖，然后口服苯那普利１０～２０ｍｇ／ｄ，４周后再行动态血压监测并复查肝、肾功能及血糖，比较治疗前后各项指标的变化。结果Ⅰ、Ⅱ期高血压患者血压呈白天高、夜间低的变化规律；Ⅲ期患者舒张压失去昼夜变化规律；苯那普利对昼夜血压均显示良好的降压效果，对肝、肾功能无不良影响。结论苯那普利具有良好的降压效果，对肝肾功能及血糖无不良影响。
Objective To observe the antihypertensive effects of benazepril and its effects on liver and renal function. Methods Forty four hypertensive patients underwent ambulatory blood pressure monitoring 24 h before treatment and liver and kidney function and blood glucose levels were measured. After oral administration of benazepril 10 to 20 mg / d for 4 weeks, ambulatory blood pressure monitoring and review of liver and kidney function and Blood sugar, compare the changes before and after treatment. Results The blood pressure of patients with stage I and II hypertension was high at daytime and low at night. The pattern of diastolic blood pressure loss in daytime and in night was abnormal. Benazepril showed good antihypertensive effect on diurnal blood pressure, Adverse effect Conclusion benazepril has a good antihypertensive effect, no adverse effects on liver and kidney function and blood glucose.