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目的:观察胃炎汤与莫沙比利联合铝碳酸镁治疗胆汁反流性胃炎的疗效对比情况。方法:将124例胆汁反流性胃炎患者随机分为观察组和对照组各62例,对照组给予枸橼酸莫沙比利与铝碳酸镁咀嚼片联合方案治疗,观察组给予胃炎汤治疗,2组均治疗2月。观察2组的治疗效果、临床症状积分和24 h反流总次数。结果:治疗总有效率观察组为91.94%,对照组为88.71%,2组比较,差异无显著性意义(P>0.05)。治疗后,2组临床症状评分和24 h反流总次数均较治疗前减少(P<0.05)。2组治疗后2项指标比较,差异均无显著性意义(P>0.05)。结论:胃炎汤治疗胆汁反流性胃炎的临床疗效与莫沙比利联合铝碳酸镁治疗方案相当,均可有效改善患者的临床症状,减少反流总次数,值得在临床推广使用。
Objective: To observe the curative effect of gastritis decoction and mosapride combined with magnesium aluminum carbonate in the treatment of bile reflux gastritis. Methods: 124 patients with bile reflux gastritis were randomly divided into observation group and control group, 62 cases in each group. The control group was treated with mosapride citrate and aluminum magnesium carbonate chewable tablets. The observation group was treated with Weiyan Decoction, 2 groups were treated in February. The therapeutic effects, clinical symptom scores and the total number of 24 h reflux were observed in the two groups. Results: The total effective rate was 91.94% in the observation group and 88.71% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, the score of clinical symptoms and the total number of 24-hour reflux were significantly lower than those before treatment (P <0.05). There was no significant difference between the two indexes in the two groups after treatment (P> 0.05). Conclusion: The clinical curative effect of gastritis decoction in the treatment of bile reflux gastritis is comparable with that of mosapride and aluminum magnesium carbonate, all of which can effectively improve the clinical symptoms of patients and reduce the total number of reflux. It is worth to be used clinically.