The protected(2S,4R)-2-amino-4-methyldecanoic acid,a proposed component of culicinins has been synthesized over 10 steps and in total 28% yields using Wittig reaction and Schllkopf amino acid synthesis as key steps. The protected (2S, 4R) -2-amino-4-methyldecanoic acid, a proposed component of culicinins has been synthesized over 10 steps and in total 28% yields using Wittig reaction and Schllkopf amino acid synthesis as key steps.