论文部分内容阅读
1990年8月至12月我们用首批国产的环丙氟哌酸(ciprofloxacin,CPLX)治疗急性细菌性痢疾(急性菌痢)30例,观察了临床近期疗效,并以同期30例急性菌痢用氟哌酸(norfloxacin,NFX)治疗作对照。均为住院病人,未经有效抗菌治疗。CPLX组及NFX组粪培养,有痢疾杆菌生长者分别为25例及27例。痊愈标准为停药后连续2天粪培养阴性,症状、体征及化验均复常者。两组口服用药剂量均0.4g 2次/d,1疗程共4天;不合用其它药。病原菌按统一药敏纸片法作平板法药敏试验,并以生物法测其最小抑菌浓度(MIC)。用药前后各查1次
From August to December 1990, we treated 30 cases of acute bacillary dysentery (acute bacillary dysentery) with the first domestic ciprofloxacin (CPLX) and observed the short-term clinical efficacy. In the same period, 30 cases of acute bacillary dysentery Norfloxacin (NFX) was used as a control. Are inpatients, without effective antibacterial treatment. CPLX group and NFX group dung culture, Shigella dysenteriae growth were 25 cases and 27 cases. The standard of cure was negative fecal culture for 2 days after discontinuation, and the symptoms, signs and tests were normal. Two groups of oral dose 0.4g 2 times / d, a course of 4 days; do not use other drugs. The pathogen according to the uniform drug susceptibility disk method for plate-based drug sensitivity test, and bioassay to determine the minimum inhibitory concentration (MIC). Check before and after treatment 1 times