自从1968年Berggard等首先从肾小管病变患者的尿中分离出β_2微球蛋白(β_2-M)后,随之有众多的学者进一步做了大量的研究工作。他们发现测定血、尿β_2-M含量可以灵敏的反映出肾小球和肾小管的功能,为临床判断肾功能的状况提供了一种可靠而简便的检查方法。为了探讨肾病综合征时血、尿β_2-M的变化,我们对113例确诊为肾病综台征的患者进行了血、尿β_2-M检查,现将结果报告如下:(一)料料和方法1.病例选择本文113例均为我院1985 Since 1968 Berggard et al first isolated β 2 microglobulin (β 2 -M) from the urine of patients with renal tubular lesion, a great many scholars have done a lot of research work. They found that determination of blood, urine β_2-M content can be sensitive to reflect the glomerular and tubular function, for the clinical judgment of renal function provides a reliable and easy way to check. In order to investigate the changes of blood and urine β_2-M in patients with nephrotic syndrome, blood and urine β_2-M were examined in 113 patients with nephrotic syndrome. The results are reported as follows: (1) Materials and Methods 1. Case Selection 113 cases were in our hospital in 1985