本文通过尾部皮肤移植技术对四个品系小鼠进行了同系异体之间、不同近交系及不同近交系的杂交F1代之间、皮肤植片100天以上的实验观察,该法不仅能够确定组织相容性基因高度纯和,还能检出用毛色基因测试法不能反应的亚系趋异,是鉴定小鼠或大鼠遗传纯度的适用方法。 In this paper, four strains of mice were tested by tail skin transplantation for more than 100 days between the F1 generation of hybrids, different inbred lines and different inbred lines, skin grafting more than 100 days. This method not only can determine Histocompatibility genes are highly pure and can also detect divergence of sublines which can not be reacted by the coat color gene test, which is a suitable method for identifying the genetic purity of mice or rats.