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目的探讨不同来源脑脓肿患者的抗感染治疗药物选择。方法收集药师参与会诊的3例脑脓肿病例,通过对诊断建立、病原菌判断、抗感染方案制订和治疗结果评价进行比较。结果 3例脑脓肿分别源于脑膜外临近组织感染,感染性心内膜炎和神经外科手术,仅有1例患者取得阳性细菌培养结果,其余2例致病菌均不明确。临床药师会诊给予治疗方案建议,监护用药过程,追踪疗效转归。3例患者均治愈出院。结论早期诊断和治疗脑脓肿会带来较好预后,抗感染治疗过程需要临床药师的参与与合作。
Objective To investigate the anti-infective treatment options in patients with different brain abscesses. Methods A total of 3 cases of brain abscess were collected from pharmacists participating in the consultation. The establishment of diagnosis, determination of pathogenic bacteria, formulation of anti-infectives and evaluation of treatment outcome were compared. Results Three cases of brain abscess were from adjacent epilepsy, infective endocarditis and neurosurgery, respectively. Only one patient had positive bacterial culture results, and the other two were unidentified. Clinical pharmacist consultation given treatment recommendations, monitoring medication process, tracking the outcome of the outcome. Three patients were cured and discharged. Conclusion Early diagnosis and treatment of brain abscess will bring better prognosis, anti-infective treatment process requires the participation of clinical pharmacists and cooperation.