糖尿病是冠心病的等危症,近年来有关冠心病与胰岛素抵抗(IR)之间关系的研究逐步深入。本文就此作一综述。1胰岛素抵抗胰岛素抵抗是指胰岛素作用的靶器官(主要是肝、肌肉、脂肪组织以及血管内皮细胞、动脉平滑肌细胞等)对胰岛素的敏感性下降,机体代偿分泌过多的胰岛素引起高胰岛素血症[1-2]。诊断胰岛素抵抗的方法有三种:(1)正常血糖胰岛素钳夹技术(euglycemic insulin clamp Diabetes mellitus is an embolism of coronary heart disease. In recent years, the research on the relationship between coronary heart disease and insulin resistance (IR) has been gradually deepened. This article gives a summary of this. 1 insulin resistance Insulin resistance refers to the insulin target organs (mainly liver, muscle, adipose tissue and vascular endothelial cells, arterial smooth muscle cells, etc.) decreased sensitivity to insulin, the body compensatory secretion of insulin caused by hyperinsulinemia Disease [1-2]. There are three ways to diagnose insulin resistance: (1) euglycemic insulin clamp