论文部分内容阅读
采用ＥＬＩＳＡ在胃肠肿瘤的手术切除组织和胃癌的胃镜活检组织中检测纤溶酶原激活剂（ＰＡｓ）抗原，结果显示癌组织中ｕ－ＰＡ含量显著高于对应的正常组织（Ｐ＜０．０１），ｔ－ＰＡ含量在肿瘤与正常组织中相似；有淋巴结转移者的癌组织中ｕ－ＰＡ含量显著高于无淋巴结转移者（Ｐ＜０．０５）；病灶较大的肿瘤组织中ｕ－ＰＡ含量与病灶小者相比差异有显著性（Ｐ＜０．０５）；分化差的癌组织中ｕ－ＰＡ含量亦高于分化好者。同一患者在活检和手术切除组织两种途径中检测ＰＡｓ抗原，结果相符。
ELISA was used to detect plasminogen activator (PAs) antigen in surgical resection tissue of gastrointestinal tumors and gastroscope biopsy of gastric cancer. The results showed that the content of u-PA in cancer tissue was significantly higher than the corresponding normal tissue (P<0. 01) t-PA content was similar in tumors and normal tissues; u-PA levels in cancer tissues with lymph node metastasis were significantly higher than those without lymph node metastasis (P<0.05); -PA content was significantly different from those with small lesions (P<0.05); u-PA content in poorly differentiated cancer tissue was also higher than that in well-differentiated ones. In the same patient, PAs antigens were detected in both biopsy and surgical excision. The results were consistent.